Clinical Research

Clinical Research Programs:
Rheumatoid Arthritis

MUSICA: Open-label Humira, studying the effects of a low or high dose of methotrexate. Efficacy tested by ultrasound.

To pre-qualify for this trial,

    you must:
  • have at least 4 swollen and tender joints.
  • currently be on an oral methotrexate dose of 15-20 mg/week for at least 12 weeks.
  • be taking prednisone. Dose must be less than 5 mg/day.
    you must not:
  • not currently be taking hydroxychloroquine, sulfasalazine, plaquenil, or leflunomide.
  • have any previous exposure to biologics.
  • have had a diagnosis of Junior Rheumatoid Arthritis.
  • have had a diagnosis of gout or pseudogout.
    This study last for six months — one visit every month, plus a screening visit.

To learn more, please call (206) 368.6135.


BATTER-UP: Biomarkers of anti-Tumor Necrosis Factor (anti-TNF) therapy efficacy in rheumatoid arthritis to define unresponsive patients. A questionnaire and blood draw only study. No drug is given.

To pre-qualify for this trial,

    you must:
  • have at least 4 swollen and tender joints.
  • be about to start treatment with your first anti-tumor necrosis factor (anti-TNF) agent or about to start a second anti-TNF agent to treat your RA.
    you must not have had any:
  • exposure to 2 or more anti-TNF agents.
  • prior exposure to Orencia, abatacept, or CTLA4-Ig, and/or Rituxan, or other biologic therapies for RA or other diseases.

    This study last for three visits:
  • Visit 1: Occurs before first dose of anti-TNF
  • Visit 2: Occurs 14 weeks after the first dose has been taken
  • Visit 3: A follow-up phone call.

To learn more, please call (206) 368.6135.

Questions?

Questions regarding research can be directed to:
Tammy Stacy
MA, CRC
(206) 368.6135