Clinical Research

Clinical Research Programs:
Systemic Lupus Erythrematosus

BUTTERFLY: A clinical study looking at a possible benefit of an investigational medication in patients with Systemic Lupus Erythematosus (SLE)

Watch a video about this study.

To pre-qualify for this trial,

    you must :
  • have had positive ANA laboratory test result
  • have active disease at the time you joint the study
  • be on stable treatment, including: methotrexate, azathioprine, leflunomide, mycophenolate, hydroxychloroquine, etc)
    you must not have had:
  • any history of treatment with PF-04236921 or other anti-interleukin 6 agent.
  • been treated with biologic investigational drugs in the last year.
  • 3 or more courses of systemic corticosteroids for other conditions (Crohn’s disease, ulcerative colititis) within the last year.
  • IV cyclophosphamide treatment within the last 180 days.
  • any anti-tumor necrosis factor agents within the last 90 days.
  • treatments for Rituxan or Benlysta.

    The study lasts for approximately 56 weeks and includes 15 clinical visits.

To learn more, please call (206) 368.6135.

Benlysta w/ Vaccine

To pre-qualify for this trial,

    you must have:
  • a positive ANA or anti-dsDNA and are receiving stable SLE therapy at screening
  • no detectable antibodies or levels below protective to tetanus toxoid and have no detectable antibodies to the pneumococcal vaccine or detectable antibodies to less than 4 of the 23 stereotypes present in the pneumococcal vaccine.
    you must not have had any:
  • prior treatment with belimumab, either as a marketed product or as an investigational agent
  • treatment with any biologic, except those indicated in exclusion criterion 3 within 364 days of Day 0
  • any of the following within 90 days of Day 0:
    • Anti-TNF therapy
    • Interleukin-1 receptor antagonist
    • Plasmapheresis
    • Corticosteroids at doses greater than or equal to 100 mg/day prednisone or equivalent

    The study will last for approximately 7 months, including 10 clinic visits.

To learn more, please call (206) 368.6135.

Questions?

Questions regarding research can be directed to:
Tammy Stacy
MA, CRC
(206) 368.6135